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They may also prolapse through the anal canal and appear as reddish, moist, protruding masses, typically located in one or more of the positions illustrated. Prolapse of the rectum on straining for a bowel movement, the rectal mucosa, with or without its muscular wall, may prolapse through the anus, appearing as a donut or rosette of red tissue. Anal fistulas abnormal tunnels join the anal canal to surrounding organs, usually other parts of the bowel. Anal stenosis the anal canal becomes abnormally narrowed either due to spasm of the anal sphincter or contraction of the resultant scar tissue. Anal cancer is a rare form of cancer that affects the tissues of the anus. We explain what you need to know about its causes and how its diagnosed. The specialist doctor will examine your anus and back passage (rectum). But if its painful, you can have the examination under general anaesthetic. Anal fistula an abnormal channel developing between the anus and the skin of the buttocks. Inflammatory bowel disease (crohns and ulcerative colitis) or previous surgery are common causes. A rectal biopsy is a procedure used to extract a tissue sample from the rectum for laboratory analysis. The rectum is the lowest 6 inches of the large intestine, located just above the anal canal. Lymph tissue under the anal inner lining (mucosa) is normal,. Sometimes abnormal cells on the inner surface layer of the anus look like cancer cells but have not grown into any of the deeper.