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What is the real cause of chronic anal itch and which remedy proves to be best. Induration means the process of increasing fibrous elements in tissue, usually connected with inflammation and a loss of elasticity and flexibility. Scleroderma is a part of systemic sclerosis, which means body-wide inside-and-out connective tissue thickening and hardening involving skin, muscles, and internal organs. 89 - includes detailed rules, notes, synonyms, icd-9-cm conversion, index and annotation crosswalks, drg grouping and more. Malignant melanoma of anal skin malignant melanoma of perianal skin melanoma, perianal skin malignant melanoma of anal margin malignant melanoma of perianal skin. chronic anal fissure was defined as clinical examination when induration at the edge was visible and horizontal fibers of the internal anal sphincter could be seen in the base of the lesion. Eight variables were studied, including scaling, erythema, fissuring, burning or itching, vesicular eruptions, edema, odor, and drainage. Gov all 1174 subjects with interdigital presentation satisfied the inclusion criteria of a minimum of moderate erythema and scaling, and mild pruritus. Cream (5) several fda-approved drug labels may be available for imiquimod. Aidsinfo provides the following drug label solely as an example of the labels available for imiquimod. Inclusion or absence of a drug label on the aidsinfo site does not imply endorsement or lack thereof by aidsinfo. Search drugsfda to access more information on imiquimod, including additional drug labels and any. In 1839, velpeau published a case report in which he described an inflammatory and abscess-forming process affecting the axillary, mammary, and perianal regions, which later was suggested to have originated in the sweat glands. 16 verneuil reported the first series of patients with this disease and gave it the name hidradenitis suppurativa. What is the real cause of chronic anal itch and which remedy proves to be best.