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Anal cancer is a cancer which arises from the anus, the distal opening of the gastrointestinal tract. Symptoms may include bleeding from the anus or a lump near the anus. Other symptoms may include pain, itchiness, or discharge from the anus. The etiology, risk factors, clinical progression, staging, and treatment are all different. Anal cancer is mostly a squamous cell carcinoma that rises near the squamocolumnar area. Other types of anal carcinoma are adenocarcinoma, lymphoma, sarcoma or melanoma. cancers of the anal canal (above the anal verge) cancers of the anal margin (below the anal verge) sometimes anal cancers extend from one area into the other, so its hard to know exactly where they started. The anal canal is surrounded by 2 sphincter muscles that keep the anus closed and prevent stool leakage. An anal sac adenocarcinoma is an uncommon and aggressive malignant tumor found in dogs that arises from the apocrine glandular tissue of anal sac. The disease exists in cats as well, but is much less common in that species. They are the second most common cancerous cause of hypercalcaemia (high serum calcium) in dogs, following t-cell lymphoma. Anal cancer incidence rates are likely to fall in future decades, according to projections accounting for the expected impact of hpv vaccination. Anal cancer in england is more common in people living in the most deprived areas. An estimated 6,700 people who had previously been diagnosed with anal cancer were alive in the uk at the end of 2010. Anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. The american society of clinical oncology estimates that 8,300 cases of anal cancer will be. treating cancers found this way is often very effective because the tumors are found early in the course of the disease. ) but most often anal cancers are found because of signs or symptoms a person is having. If anal cancer is suspected, exams and tests will be needed to confirm the diagnosis. Colorectal cancer (crc), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and feeling tired all the time. Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases.